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Relavent Articles (Editor's Choice)A Caenorhabditis elegans genetic-interaction map wiggles into view.Gunsalus KC.Systematic mapping of genetic-interaction networks will provide an essential foundation for understanding complex genetic disorders, mechanisms of genetic buffering and principles of robustness and evolvability. A recent study of signaling pathways in Caenorhabditis elegans lays the next row of bricks in this foundation. Journal: J Biol. 2008;7(3):8. Assessing the Validity and Applicability Domain of QSAR ModelsAmit I, Wides R, Yarden Y.Robust biological signaling networks evolved, through gene duplications, from simple, relatively fragile cascades. Architectural features such as layered configuration, branching and modularity, as well as functional characteristics (e.g., feedback control circuits), enable fail-safe performance in the face of internal.... Journal: Mol Syst Biol. 2007;3:151. [1] [2] [3] ... View Archives Editor's Note:The literature section highlights current exciting papers in the field of genomics research today. These papers have been selected by experts from Strand Life Sciences. We will update this section fortnightly to keep abreast with the most recent publications. Last Updated: 7th Aug. 2008 |
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