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Literature

Will feature expert opinions and guest columns from a panel of relevant scientists. It will also host the editor’s choice of article of the month, which will be a pioneering publication in the field. Web links will be provided to all relevant publications, subject to the editor’s discretion. Reader will find this site useful to be up-to-date on the current work in the field and familiarize with the emerging concepts of network biology.




Relavent Articles (Editor's Choice)

A Caenorhabditis elegans genetic-interaction map wiggles into view.

Gunsalus KC.

Systematic mapping of genetic-interaction networks will provide an essential foundation for understanding complex genetic disorders, mechanisms of genetic buffering and principles of robustness and evolvability. A recent study of signaling pathways in Caenorhabditis elegans lays the next row of bricks in this foundation.

Journal:   J Biol. 2008;7(3):8.




Assessing the Validity and Applicability Domain of QSAR Models

Amit I, Wides R, Yarden Y.

Robust biological signaling networks evolved, through gene duplications, from simple, relatively fragile cascades. Architectural features such as layered configuration, branching and modularity, as well as functional characteristics (e.g., feedback control circuits), enable fail-safe performance in the face of internal....

Journal:   Mol Syst Biol. 2007;3:151.



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Editor's Note:

The literature section highlights current exciting papers in the field of genomics research today. These papers have been selected by experts from Strand Life Sciences. We will update this section fortnightly to keep abreast with the most recent publications.

Last Updated:   7th Aug. 2008

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