'Pathway Search Results'

Selection criteria for significant gene list :: Significant genes are selected with a p value cut-off of 0.1. The resultant list was then sorted in a descending order of fold change value. From the sorted list, the top 100 genes were selected for pathway/network. If the gene list is less than 100, the entire gene list was taken for pathway/network analysis.

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>>Total hits : 11 , Search term given : Asthma

Asthma and atopy (HG-U133B)

GEO Description :
Investigation of CD4+ lymphocytes from patients with and without atopy, in combination with asthma.
Organism : Homo sapiens
GEO-ID : GDS267

Compared Group :
no asthma Vs mild asthma

Number of Nodes in the Network : 2
Number of Nodes passing Cut-Off : 100
PValue Cut-Off : 0.00110703962855041
Fold Change Cut-Off : 2.4

Compared Group :
severe asthma Vs mild asthma

Number of Nodes in the Network : 21
Number of Nodes passing Cut-Off : 100
PValue Cut-Off : 0.000106036291981582
Fold Change Cut-Off : 2.23

Compared Group :
no atopy Vs atopy

Number of Nodes in the Network : 18
Number of Nodes passing Cut-Off : 100
PValue Cut-Off : 0.0057387393899262
Fold Change Cut-Off : 2.0

Asthma and interleukin 13 (MOE430A)

GEO Description :
Expression profiling of lung tissue from interleukin 13 (IL-13) knockout mice treated with house dust mite allergen. IL-13 mediates the development of asthma by causing hyperreactivity of the airway and mucus overproduction in the lung.
Organism : Mus musculus
GEO-ID : GDS958

Compared Group :
control Vs allergen

Number of Nodes in the Network : 35
Number of Nodes passing Cut-Off : 100
PValue Cut-Off : 1.07831956697169e-08
Fold Change Cut-Off : 2.01

Compared Group :
wild type Vs IL-13 knockout

Number of Nodes in the Network : 22
Number of Nodes passing Cut-Off : 100
PValue Cut-Off : 2.6889591026702e-05
Fold Change Cut-Off : 2.02

Interleukin 13 effect on bronchial cell line: time course

GEO Description :
Analysis of bronchial A549 cells at various time points up to 24 hours following treatment with the cytokine interleukin 13 (IL-13). IL-13 contributes to the pathogenesis of asthma.
Organism : Homo sapiens
GEO-ID : GDS2852

Compared Group :
control Vs IL-13

Number of Nodes in the Network : 41
Number of Nodes passing Cut-Off : 100
PValue Cut-Off : 5.13091833909129e-07
Fold Change Cut-Off : 2.14

Compared Group :
0 h Vs 12 h

Number of Nodes in the Network : 32
Number of Nodes passing Cut-Off : 100
PValue Cut-Off : 0.000498473236802965
Fold Change Cut-Off : 2.12

Compared Group :
0 h Vs 24 h

Number of Nodes in the Network : 45
Number of Nodes passing Cut-Off : 100
PValue Cut-Off : 2.30946116062114e-05
Fold Change Cut-Off : 2.09

Asthma and interleukin 13 (MOE430B)

GEO Description :
Expression profiling of lung tissue from interleukin 13 (IL-13) knockout mice treated with house dust mite allergen. IL-13 mediates the development of asthma by causing hyperreactivity of the airway and mucus overproduction in the lung.
Organism : Mus musculus
GEO-ID : GDS959

Compared Group :
wild type Vs IL-13 knockout

Number of Nodes in the Network : 6
Number of Nodes passing Cut-Off : 100
PValue Cut-Off : 2.5240160539397e-05
Fold Change Cut-Off : 2.04

Compared Group :
control Vs allergen

Number of Nodes in the Network : 15
Number of Nodes passing Cut-Off : 100
PValue Cut-Off : 1.22577478123276e-06
Fold Change Cut-Off : 2.19

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The interactions, networks, list of genes/molecules or any other information presented here, is HYPOTHETICAL in nature and is based on information collected from public as well as other sources, and is analyzed by certain automated mining and analysis software workflows. Strandlife Science Pvt.Ltd. or the Editors of PathwayWorld offer this information with NO CLAIMS of accuracy and WARRANTIES of any kind, and DO NOT Accept liability or legal responsibility for losses allegedly caused by using this information.

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