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Analysis Pipeline


'Pathway Search Results'

Selection criteria for significant gene list :
Significant genes are selected with a p value cut-off of 0.1. The resultant list was then sorted in a descending order of fold change value. From the sorted list, the top 100 genes were selected for pathway/network. If the gene list is less than 100, the entire gene list was taken for pathway/network analysis.

>>Total hits : 9 , Search term given : B-cell

  Fibroblast adipogenesis induced by EBF-1 and PPARgamma2 overexpression: time course

GEO Description :
Analysis of NIH-3T3 embryonic fibroblasts induced to differentiate into adipocytes by overexpression of early B cell factor (EBF)-1 or peroxisome proliferator-activated receptor (PPAR)gamma2 transcription factors. Cells examined at various time points up to 10 days following overexpression.
Organism : Mus musculus
GEO-ID : GDS1298

Compared Group :
0 d Vs 10 d
  • Number of Nodes in the Network : 39
  • Number of Nodes passing Cut-Off : 100
  • PValue Cut-Off : 2.53803835587041e-12
  • Fold Change Cut-Off : 2.19
Compared Group :
control Vs PPARgamma2
  • Number of Nodes in the Network : 49
  • Number of Nodes passing Cut-Off : 100
  • PValue Cut-Off : 3.28797909787681e-07
  • Fold Change Cut-Off : 2.35
Compared Group :
0 d Vs 4 d
  • Number of Nodes in the Network : 44
  • Number of Nodes passing Cut-Off : 100
  • PValue Cut-Off : 1.13406320617146e-21
  • Fold Change Cut-Off : 2.22
Compared Group :
control Vs EBF-1
  • Number of Nodes in the Network : 25
  • Number of Nodes passing Cut-Off : 100
  • PValue Cut-Off : 3.45590604744483e-11
  • Fold Change Cut-Off : 2.42
Compared Group :
0 d Vs 2 d
  • Number of Nodes in the Network : 48
  • Number of Nodes passing Cut-Off : 100
  • PValue Cut-Off : 4.92886011144955e-19
  • Fold Change Cut-Off : 2.24

  Follicular dendritic cell enriched splenocytes (MG U74C)

GEO Description :
Analysis of follicular dendritic cell (FDCs) enriched splenocytes. FDCs are important in the formation of lymphoid germinal centers (GCs), where rapid B-cell proliferation and differentiation occur. Results identify transcripts that are overrepresented in cells associated with FDC networks in GCs.
Organism : Mus musculus
GEO-ID : GDS1600

Compared Group :
follicular dendritic cell-depleted splenocytes Vs follicular dendritic cell-enriched splenocytes
  • Number of Nodes in the Network : 10
  • Number of Nodes passing Cut-Off : 100
  • PValue Cut-Off : 6.0877046053065e-05
  • Fold Change Cut-Off : 2.09

  Follicular dendritic cell enriched splenocytes (MG U74B)

GEO Description :
Analysis of follicular dendritic cell (FDCs) enriched splenocytes. FDCs are important in the formation of lymphoid germinal centers (GCs), where rapid B-cell proliferation and differentiation occur. Results identify transcripts that are overrepresented in cells associated with FDC networks in GCs.
Organism : Mus musculus
GEO-ID : GDS1599

Compared Group :
follicular dendritic cell-depleted splenocytes Vs follicular dendritic cell-enriched splenocytes
  • Number of Nodes in the Network : 9
  • Number of Nodes passing Cut-Off : 100
  • PValue Cut-Off : 1.10357368612313e-05
  • Fold Change Cut-Off : 2.95

  Follicular dendritic cell enriched splenocytes (MG U74A)

GEO Description :
Analysis of follicular dendritic cell (FDCs) enriched splenocytes. FDCs are important in the formation of lymphoid germinal centers (GCs), where rapid B-cell proliferation and differentiation occur. Results identify transcripts that are overrepresented in cells associated with FDC networks in GCs.
Organism : Mus musculus
GEO-ID : GDS1585

Compared Group :
follicular dendritic cell-depleted splenocytes Vs follicular dendritic cell-enriched splenocytes
  • Number of Nodes in the Network : 60
  • Number of Nodes passing Cut-Off : 100
  • PValue Cut-Off : 5.83951032240293e-06
  • Fold Change Cut-Off : 3.55

  T-cell acute lymphoblastic leukemia and T-cell lymphoblastic lymphoma comparison

GEO Description :
Comparison of expression profiles in T-cell acute lymphoblastic leukemia (T-ALL) to that in T-cell lymphoblastic lymphoma (T-LL). Gene expression in B-precursor acute lymphoblastic leukemia also examined. Results provide insight into the molecular basis for the difference between T-ALL and T-LL.
Organism : Homo sapiens
GEO-ID : GDS760

Compared Group :
T-cell lymphoblastic lymphoma Vs T-cell acute lymphoblastic leukemia
  • Number of Nodes in the Network : 32
  • Number of Nodes passing Cut-Off : 100
  • PValue Cut-Off : 5.41823738653413e-11
  • Fold Change Cut-Off : 2.08







DISCLAIMER:
The interactions, networks, list of genes/molecules or any other information presented here, is HYPOTHETICAL in nature and is based on information collected from public as well as other sources, and is analyzed by certain automated mining and analysis software workflows. Strandlife Science Pvt.Ltd. or the Editors of PathwayWorld offer this information with NO CLAIMS of accuracy and WARRANTIES of any kind, and DO NOT Accept liability or legal responsibility for losses allegedly caused by using this information.

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