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'Pathway Search Results'
- Selection criteria for significant gene list :
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Significant genes are selected with a p value cut-off of 0.1. The resultant list was then sorted in a descending order of fold change value. From the sorted list, the top 100 genes were selected for pathway/network. If the gene list is less than 100, the entire gene list was taken for pathway/network analysis.
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>>Total hits : 9
, Search term given : Cardiomyopathy
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Dilated cardiomyopathy: left ventricle
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GEO Description :
Comparison of subendocardial left ventricular tissue samples from 7 patients with dilated cardiomyopathy (DCM) to those from 5 patients with non-failing (NF) hearts. DCM is a common cause of heart failure. Results contribute to the identification of a gene expression signature for DCM.
Organism : Homo sapiens
GEO-ID : GDS2205
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- Compared Group :
- non-failing Vs dilated cardiomyopathy
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- Number of Nodes in the Network : 37
- Number of Nodes passing Cut-Off : 100
- PValue Cut-Off : 1.91685558093013e-05
- Fold Change Cut-Off : 2.35
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Diabetic cardiomyopathy progression model
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GEO Description :
Analysis of ventricles of streptozotocin-induced diabetic animals with early diabetic cardiomyopathy (DC) characterized by diastolic dysfunction (DD) or late DC characterized by DD and systolic dysfunction (SD). Results provide insight into mechanisms underlying DD and SD development in diabetes.
Organism : Rattus norvegicus
GEO-ID : GDS2132
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- Compared Group :
- control Vs streptozotocin
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- Number of Nodes in the Network : 35
- Number of Nodes passing Cut-Off : 100
- PValue Cut-Off : 8.2313315885596e-11
- Fold Change Cut-Off : 2.26
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- Compared Group :
- 3 d Vs 48 d
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- Number of Nodes in the Network : 32
- Number of Nodes passing Cut-Off : 100
- PValue Cut-Off : 2.6634880412324e-10
- Fold Change Cut-Off : 2.34
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- Compared Group :
- 3 d Vs 28 d
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- Number of Nodes in the Network : 44
- Number of Nodes passing Cut-Off : 100
- PValue Cut-Off : 1.29736974940897e-06
- Fold Change Cut-Off : 2.0
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- Compared Group :
- baseline Vs control
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- Number of Nodes in the Network : 35
- Number of Nodes passing Cut-Off : 100
- PValue Cut-Off : 8.93397896106762e-07
- Fold Change Cut-Off : 2.46
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- Compared Group :
- baseline Vs systolic and diastolic dysfunction
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- Number of Nodes in the Network : 36
- Number of Nodes passing Cut-Off : 100
- PValue Cut-Off : 5.93673539697193e-05
- Fold Change Cut-Off : 2.12
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- Compared Group :
- 48 d Vs 28 d
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- Number of Nodes in the Network : 8
- Number of Nodes passing Cut-Off : 100
- PValue Cut-Off : 1.88179598126226e-07
- Fold Change Cut-Off : 2.33
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- Compared Group :
- baseline Vs diastolic dysfunction
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- Number of Nodes in the Network : 36
- Number of Nodes passing Cut-Off : 100
- PValue Cut-Off : 0.000321447179885581
- Fold Change Cut-Off : 2.68
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Exercise effect on the diabetic cardiac muscle: time course
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GEO Description :
Analysis of experimental type 1 diabetic cardiac muscles of NMRI males subjected to endurance training for up to 5 weeks. Diabetes induced by a single peritoneal injection of streptozotocin.
Organism : Mus musculus
GEO-ID : GDS2335
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- Compared Group :
- training Vs sedentary
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- Number of Nodes in the Network : 16
- Number of Nodes passing Cut-Off : 100
- PValue Cut-Off : 0.000410816981457174
- Fold Change Cut-Off : 2.13
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DISCLAIMER:
The interactions, networks, list of genes/molecules or any other information presented here, is HYPOTHETICAL in nature and is based on information collected from public as well as other sources, and is analyzed by certain automated mining and analysis software workflows. Strandlife Science Pvt.Ltd. or the Editors of PathwayWorld offer this information with NO CLAIMS of accuracy and WARRANTIES of any kind, and DO NOT Accept liability or legal responsibility for losses allegedly caused by using this information.
GeneSpring® is a registered trademark of Agilent Technologies.
GeneSpring® is developed on AVADIS™ from Strand Life Sciences
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