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Analysis Pipeline


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Selection criteria for significant gene list :
Significant genes are selected with a p value cut-off of 0.1. The resultant list was then sorted in a descending order of fold change value. From the sorted list, the top 100 genes were selected for pathway/network. If the gene list is less than 100, the entire gene list was taken for pathway/network analysis.
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>>Total hits : 28 , Search term given : Cerebellum

  Inbred Long Sleep and Inbred Short Sleep model of ethanol sensitivity: cerebellum (MG-430A)

GEO Description :
Comparison of cerebella of Inbred Long Sleep (ILS) and Inbred Short Sleep (ISS) animals. ILS animals are more sensitive than ISS animals to ethanol. Initial sensitivity to ethanol is a predictor of alcohol abuse. Results provide insight into the molecular basis of differential ethanol sensitivity.
Organism : Mus musculus
GEO-ID : GDS1609

Compared Group :
Inbred Long Sleep Vs Inbred Short Sleep
  • Number of Nodes in the Network : 6
  • Number of Nodes passing Cut-Off : 100
  • PValue Cut-Off : 6.65377083350904e-05
  • Fold Change Cut-Off : 2.02

  Nuclear and extranuclear mutant huntingtin exon 1 protein effect on cerebellum

GEO Description :
Analysis of cerebella of transgenics expressing mutant huntingtin (htt) exon 1 protein in nucleus only or in both nucleus and cytoplasm. The polyglutamine (polyQ) expansion in htt results in Huntington's disease (HD). Results provide insight into the impact of subcellular location of polyQ in HD.
Organism : Mus musculus
GEO-ID : GDS2169

Compared Group :
10 m Vs 4 m
  • Number of Nodes in the Network : 15
  • Number of Nodes passing Cut-Off : 100
  • PValue Cut-Off : 0.000199239686480723
  • Fold Change Cut-Off : 2.03
Compared Group :
transgenic A61 Vs transgenic A39
  • Number of Nodes in the Network : 10
  • Number of Nodes passing Cut-Off : 100
  • PValue Cut-Off : 3.17740305035841e-05
  • Fold Change Cut-Off : 2.02
Compared Group :
3 m Vs 10 m
  • Number of Nodes in the Network : 16
  • Number of Nodes passing Cut-Off : 100
  • PValue Cut-Off : 4.82927156042479e-08
  • Fold Change Cut-Off : 2.02
Compared Group :
3.5 m Vs 16 m
  • Number of Nodes in the Network : 21
  • Number of Nodes passing Cut-Off : 100
  • PValue Cut-Off : 1.71959470662841e-07
  • Fold Change Cut-Off : 2.0
Compared Group :
transgenic A61 Vs transgenic x50
  • Number of Nodes in the Network : 35
  • Number of Nodes passing Cut-Off : 100
  • PValue Cut-Off : 2.76633272733307e-07
  • Fold Change Cut-Off : 2.05
Compared Group :
3.5 m Vs 4 m
  • Number of Nodes in the Network : 17
  • Number of Nodes passing Cut-Off : 100
  • PValue Cut-Off : 5.52955225430196e-06
  • Fold Change Cut-Off : 2.09
Compared Group :
transgenic x50 Vs transgenic S46
  • Number of Nodes in the Network : 31
  • Number of Nodes passing Cut-Off : 100
  • PValue Cut-Off : 4.09851651284043e-07
  • Fold Change Cut-Off : 2.03
Compared Group :
8 m Vs 3.5 m
  • Number of Nodes in the Network : 19
  • Number of Nodes passing Cut-Off : 100
  • PValue Cut-Off : 2.5069311959669e-07
  • Fold Change Cut-Off : 2.04
Compared Group :
10 m Vs 3.5 m
  • Number of Nodes in the Network : 17
  • Number of Nodes passing Cut-Off : 100
  • PValue Cut-Off : 1.11574927075253e-07
  • Fold Change Cut-Off : 2.06







DISCLAIMER:
The interactions, networks, list of genes/molecules or any other information presented here, is HYPOTHETICAL in nature and is based on information collected from public as well as other sources, and is analyzed by certain automated mining and analysis software workflows. Strandlife Science Pvt.Ltd. or the Editors of PathwayWorld offer this information with NO CLAIMS of accuracy and WARRANTIES of any kind, and DO NOT Accept liability or legal responsibility for losses allegedly caused by using this information.

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