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'Pathway Search Results'
- Selection criteria for significant gene list :
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Significant genes are selected with a p value cut-off of 0.1. The resultant list was then sorted in a descending order of fold change value. From the sorted list, the top 100 genes were selected for pathway/network. If the gene list is less than 100, the entire gene list was taken for pathway/network analysis.
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>>Total hits : 2
, Search term given : Chronic AND Obstructive AND Pulmonary AND Disease
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Chronic obstructive pulmonary disease
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GEO Description : Study of the signaling mechanisms responsible for diaphragm muscle transformation from fast-to-slow fiber type in chronic obstructive pulmonary disease (COPD) patients.
Organism : Homo sapiens
GEO-ID : GDS289
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- Compared Group :
- control Vs chronic obstructive pulmonary disease
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- Number of Nodes in the Network : 29
- Number of Nodes passing Cut-Off : 100
- PValue Cut-Off : 0.0107316449284554
- Fold Change Cut-Off : 2.3
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Cigarette smoking effect on alveolar macrophages
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GEO Description : Anlaysis of alveolar macrophages of 5 phenotypically normal smokers who consume ~20 packs cigarettes/year. Smoking is the leading cause of respiratory diseases collectively known as chronic obstructive pulmonary disease (COPD). Provides insight into early events in molecular pathogenesis of COPD.
Organism : Homo sapiens
GEO-ID : GDS1436
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- Compared Group :
- non-smoker Vs smoker
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- Number of Nodes in the Network : 38
- Number of Nodes passing Cut-Off : 100
- PValue Cut-Off : 0.000943616963922977
- Fold Change Cut-Off : 2.09
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DISCLAIMER: The interactions, networks, list of genes/molecules or any other information presented here, is HYPOTHETICAL in nature and is based on information collected from public as well as other sources, and is analyzed by certain automated mining and analysis software workflows. Strandlife Science Pvt.Ltd. or the Editors of PathwayWorld offer this information with NO CLAIMS of accuracy and WARRANTIES of any kind, and DO NOT Accept liability or legal responsibility for losses allegedly caused by using this information.
GeneSpring® is a registered trademark of Agilent Technologies. GeneSpring® is developed on AVADIS from Strand Life Sciences
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