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'Pathway Search Results'
- Selection criteria for significant gene list :
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Significant genes are selected with a p value cut-off of 0.1. The resultant list was then sorted in a descending order of fold change value. From the sorted list, the top 100 genes were selected for pathway/network. If the gene list is less than 100, the entire gene list was taken for pathway/network analysis.
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>>Total hits : 8
, Search term given : Hepatocarcinoma
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Arginine deprivation effect on tumorigenic hepatic cells
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GEO Description :
Analysis of neoplastic hepatic cells subjected to arginine deprivation. Results identify arginine responsive genes that become unresponsive to arginine in tumorigenic cells.
Organism : Rattus norvegicus
GEO-ID : GDS1622
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- Compared Group :
- control Vs arginine deprivation
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- Number of Nodes in the Network : 20
- Number of Nodes passing Cut-Off : 100
- PValue Cut-Off : 2.47331645368831e-05
- Fold Change Cut-Off : 2.16
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- Compared Group :
- normal Vs tumorigenic
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- Number of Nodes in the Network : 23
- Number of Nodes passing Cut-Off : 100
- PValue Cut-Off : 1.34257452377717e-10
- Fold Change Cut-Off : 2.79
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PPAR? agonist ciprofibrate effect on liver
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GEO Description :
Analysis of primate livers exposed to ciprofibrate at various doses for 4 or 15 days. Peroxisome proliferator-activated receptor-? (PPAR?) agonists such as ciprofibrate cause hepatocarcinogenesis in rodents but not in primates. Results identify species differences in response to PPAR? agonist.
Organism : Macaca fascicularis, Homo sapiens
GEO-ID : GDS1442
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- Compared Group :
- control Vs ciprofibrate
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- Number of Nodes in the Network : 51
- Number of Nodes passing Cut-Off : 100
- PValue Cut-Off : 2.33977925745421e-06
- Fold Change Cut-Off : 2.33
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- Compared Group :
- 0 mg/kg/day Vs 150 mg/kg/day
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- Number of Nodes in the Network : 47
- Number of Nodes passing Cut-Off : 100
- PValue Cut-Off : 7.59341783123091e-05
- Fold Change Cut-Off : 2.09
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- Compared Group :
- 0 mg/kg/day Vs 30 mg/kg/day
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- Number of Nodes in the Network : 44
- Number of Nodes passing Cut-Off : 100
- PValue Cut-Off : 0.000127115854411386
- Fold Change Cut-Off : 2.0
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- Compared Group :
- 0 mg/kg/day Vs 400 mg/kg/day
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- Number of Nodes in the Network : 51
- Number of Nodes passing Cut-Off : 100
- PValue Cut-Off : 1.15514853860077e-06
- Fold Change Cut-Off : 2.02
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- Compared Group :
- 0 mg/kg/day Vs 3 mg/kg/day
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- Number of Nodes in the Network : 43
- Number of Nodes passing Cut-Off : 100
- PValue Cut-Off : 4.89974299853202e-05
- Fold Change Cut-Off : 2.22
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- Compared Group :
- 4 days Vs 15 days
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- Number of Nodes in the Network : 40
- Number of Nodes passing Cut-Off : 100
- PValue Cut-Off : 1.54614554492838e-09
- Fold Change Cut-Off : 2.01
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DISCLAIMER:
The interactions, networks, list of genes/molecules or any other information presented here, is HYPOTHETICAL in nature and is based on information collected from public as well as other sources, and is analyzed by certain automated mining and analysis software workflows. Strandlife Science Pvt.Ltd. or the Editors of PathwayWorld offer this information with NO CLAIMS of accuracy and WARRANTIES of any kind, and DO NOT Accept liability or legal responsibility for losses allegedly caused by using this information.
GeneSpring® is a registered trademark of Agilent Technologies.
GeneSpring® is developed on AVADIS™ from Strand Life Sciences
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