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'Pathway Search Results'
- Selection criteria for significant gene list :
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Significant genes are selected with a p value cut-off of 0.1. The resultant list was then sorted in a descending order of fold change value. From the sorted list, the top 100 genes were selected for pathway/network. If the gene list is less than 100, the entire gene list was taken for pathway/network analysis.
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>>Total hits : 2
, Search term given : Hypercholesterolemia
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Stearoyl-CoA desaturase 1-deficient mutants on a very low-fat, high-carbohydrate diet: liver expression profile
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GEO Description :
Analysis of liver from stearoyl-CoA desaturase 1 (SCD1) deficient mutants maintained on a very low-fat, high-carbohydrate (VLF-HC) diet. SCD1-deficient mutants on VLF-HC develop severe hypercholesterolemia, have reduced high-density lipoprotein cholesterol, and hepatic dysfunction.
Organism : Mus musculus
GEO-ID : GDS1517
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- Compared Group :
- wild type Vs Scd1 null
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- Number of Nodes in the Network : 23
- Number of Nodes passing Cut-Off : 100
- PValue Cut-Off : 7.06781793269329e-05
- Fold Change Cut-Off : 3.44
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- Compared Group :
- control Vs low fat, high carbohydrate
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- Number of Nodes in the Network : 11
- Number of Nodes passing Cut-Off : 100
- PValue Cut-Off : 1.86447062758451e-13
- Fold Change Cut-Off : 3.63
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DISCLAIMER:
The interactions, networks, list of genes/molecules or any other information presented here, is HYPOTHETICAL in nature and is based on information collected from public as well as other sources, and is analyzed by certain automated mining and analysis software workflows. Strandlife Science Pvt.Ltd. or the Editors of PathwayWorld offer this information with NO CLAIMS of accuracy and WARRANTIES of any kind, and DO NOT Accept liability or legal responsibility for losses allegedly caused by using this information.
GeneSpring® is a registered trademark of Agilent Technologies.
GeneSpring® is developed on AVADIS™ from Strand Life Sciences
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