'Pathway Search Results'

Selection criteria for significant gene list :: Significant genes are selected with a p value cut-off of 0.1. The resultant list was then sorted in a descending order of fold change value. From the sorted list, the top 100 genes were selected for pathway/network. If the gene list is less than 100, the entire gene list was taken for pathway/network analysis.

>>Total hits : 1 , Search term given : Mitochondrial AND Diseases

Uterine fibroids with fumarate hydratase mutations

GEO Description :
Analysis of 7 uterine fibroids carrying fumarate hydratase (FH) mutations. FH catalyzes hydration of fumarate in the Krebs tricarboxylic acid cycle. Results provide insight into the connection between the disruption of mitochondrial metabolic pathways and neoplasia.
Organism : Homo sapiens
GEO-ID : GDS1476

Compared Group :
wild type fumarate hydratase Vs mutant fumarate hydratase

Number of Nodes in the Network : 26
Number of Nodes passing Cut-Off : 100
PValue Cut-Off : 0.000201369723072276
Fold Change Cut-Off : 2.01

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The interactions, networks, list of genes/molecules or any other information presented here, is HYPOTHETICAL in nature and is based on information collected from public as well as other sources, and is analyzed by certain automated mining and analysis software workflows. Strandlife Science Pvt.Ltd. or the Editors of PathwayWorld offer this information with NO CLAIMS of accuracy and WARRANTIES of any kind, and DO NOT Accept liability or legal responsibility for losses allegedly caused by using this information.

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