'Pathway Search Results'

Selection criteria for significant gene list :: Significant genes are selected with a p value cut-off of 0.1. The resultant list was then sorted in a descending order of fold change value. From the sorted list, the top 100 genes were selected for pathway/network. If the gene list is less than 100, the entire gene list was taken for pathway/network analysis.

>>Total hits : 4 , Search term given : Polycystic AND Ovary AND Syndrome

Valproic acid effect on theca cells (HG-U133B)

GEO Description :
Analysis of normal theca cells treated with 500 uM valproic acid (VPA), an anti-epilipetic that induces polycystic ovary syndrome (PCOS)-like symptoms. Theca cells from PCOS patients also examined. Results provide insight into the underlying mechanisms contributing to VPA-induced PCOS-like symptoms.
Organism : Homo sapiens
GEO-ID : GDS1051

Compared Group :
normal Vs polycystic ovary syndrome

Number of Nodes in the Network : 6
Number of Nodes passing Cut-Off : 100
PValue Cut-Off : 1.10299870357267e-05
Fold Change Cut-Off : 2.14

Compared Group :
valproic acid Vs untreated

Number of Nodes in the Network : 10
Number of Nodes passing Cut-Off : 100
PValue Cut-Off : 2.52047243520792e-06
Fold Change Cut-Off : 2.25

Valproic acid effect on theca cells (HG-U133A)

GEO Description :
Analysis of normal theca cells treated with 500 uM valproic acid (VPA), an anti-epilipetic that induces polycystic ovary syndrome (PCOS)-like symptoms. Theca cells from PCOS patients also examined. Results provide insight into the underlying mechanisms contributing to VPA-induced PCOS-like symptoms.
Organism : Homo sapiens
GEO-ID : GDS1050

Compared Group :
polycystic ovary syndrome Vs normal

Number of Nodes in the Network : 41
Number of Nodes passing Cut-Off : 100
PValue Cut-Off : 1.49712406027902e-07
Fold Change Cut-Off : 2.31

Compared Group :
valproic acid Vs untreated

Number of Nodes in the Network : 38
Number of Nodes passing Cut-Off : 100
PValue Cut-Off : 1.65658384787548e-08
Fold Change Cut-Off : 3.03

DISCLAIMER:
The interactions, networks, list of genes/molecules or any other information presented here, is HYPOTHETICAL in nature and is based on information collected from public as well as other sources, and is analyzed by certain automated mining and analysis software workflows. Strandlife Science Pvt.Ltd. or the Editors of PathwayWorld offer this information with NO CLAIMS of accuracy and WARRANTIES of any kind, and DO NOT Accept liability or legal responsibility for losses allegedly caused by using this information.

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