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Analysis Pipeline


'Pathway Search Results'

Selection criteria for significant gene list :
Significant genes are selected with a p value cut-off of 0.1. The resultant list was then sorted in a descending order of fold change value. From the sorted list, the top 100 genes were selected for pathway/network. If the gene list is less than 100, the entire gene list was taken for pathway/network analysis.

>>Total hits : 2 , Search term given : Rheumatic AND Diseases

  Juvenile rheumatoid arthritis expression profiles in mononuclear cells

GEO Description :
Examination of peripheral blood and synovial fluid mononuclear cells in pauciarticular and polyarticular rheumatoid arthritis, and in juvenile spondyloarthropathy. Results identify disease subtypes and provide insight into disease mechanisms.
Organism : Homo sapiens
GEO-ID : GDS711

Compared Group :
normal Vs spondyloarthropathy
  • Number of Nodes in the Network : 57
  • Number of Nodes passing Cut-Off : 100
  • PValue Cut-Off : 1.6631940525258e-05
  • Fold Change Cut-Off : 2.4

  D-penicillamine-induced autoimmunity model of idiosyncratic drug reactions

GEO Description :
Analysis of Brown Norway males 6 hours after treatment with 150 mg/kg of D-penicillamine. Some rheumatoid arthritis patients treated with D-penicillamine develop idiosyncratic drug reactions (IDR). Results provide insight into mechanisms underlying IDR.
Organism : Rattus norvegicus
GEO-ID : GDS1394

Compared Group :
control Vs D-penicillamine
  • Number of Nodes in the Network : 12
  • Number of Nodes passing Cut-Off : 100
  • PValue Cut-Off : 0.000122871468192898
  • Fold Change Cut-Off : 2.0







DISCLAIMER:
The interactions, networks, list of genes/molecules or any other information presented here, is HYPOTHETICAL in nature and is based on information collected from public as well as other sources, and is analyzed by certain automated mining and analysis software workflows. Strandlife Science Pvt.Ltd. or the Editors of PathwayWorld offer this information with NO CLAIMS of accuracy and WARRANTIES of any kind, and DO NOT Accept liability or legal responsibility for losses allegedly caused by using this information.

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