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'Pathway Search Results'
- Selection criteria for significant gene list :
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Significant genes are selected with a p value cut-off of 0.1. The resultant list was then sorted in a descending order of fold change value. From the sorted list, the top 100 genes were selected for pathway/network. If the gene list is less than 100, the entire gene list was taken for pathway/network analysis.
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>>Total hits : 15
, Search term given : T-cell
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Next>>
T-cell acute lymphoblastic leukemia and T-cell lymphoblastic lymphoma comparison
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GEO Description :
Comparison of expression profiles in T-cell acute lymphoblastic leukemia (T-ALL) to that in T-cell lymphoblastic lymphoma (T-LL). Gene expression in B-precursor acute lymphoblastic leukemia also examined. Results provide insight into the molecular basis for the difference between T-ALL and T-LL.
Organism : Homo sapiens
GEO-ID : GDS760
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- Compared Group :
- T-cell lymphoblastic lymphoma Vs T-cell acute lymphoblastic leukemia
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- Number of Nodes in the Network : 32
- Number of Nodes passing Cut-Off : 100
- PValue Cut-Off : 5.41823738653413e-11
- Fold Change Cut-Off : 2.08
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- Compared Group :
- T-cell acute lymphoblastic leukemia Vs B-precursor acute lymphoblastic leukemia
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- Number of Nodes in the Network : 29
- Number of Nodes passing Cut-Off : 100
- PValue Cut-Off : 9.60966062280022e-08
- Fold Change Cut-Off : 2.12
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- Compared Group :
- T-cell lymphoblastic lymphoma Vs B-precursor acute lymphoblastic leukemia
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- Number of Nodes in the Network : 30
- Number of Nodes passing Cut-Off : 100
- PValue Cut-Off : 2.1550544682114e-10
- Fold Change Cut-Off : 2.03
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- Compared Group :
- bone marrow Vs lymphoid
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- Number of Nodes in the Network : 29
- Number of Nodes passing Cut-Off : 100
- PValue Cut-Off : 5.58490563908401e-14
- Fold Change Cut-Off : 2.64
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Positively selected H-2b T cell receptor transgenic thymocytes (MG-U74C)
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GEO Description :
Analysis of positively selected T cell receptor (TCR) transgenic thymocytes from H-2b animals. T lymphocyte development involves TCR-mediated positive selection that ensures the survival of potentially useful T cells. Results provide insight into T lymphocyte development and selection.
Organism : Mus musculus
GEO-ID : GDS1936
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- Compared Group :
- wild type Vs TCR transgenic
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- Number of Nodes in the Network : 54
- Number of Nodes passing Cut-Off : 97
- PValue Cut-Off : 0.000176492831087671
- Fold Change Cut-Off : 2.09
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Positively selected H-2b T cell receptor transgenic thymocytes (MG-U74B)
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GEO Description :
Analysis of positively selected T cell receptor (TCR) transgenic thymocytes from H-2b animals. T lymphocyte development involves TCR-mediated positive selection that ensures the survival of potentially useful T cells. Results provide insight into T lymphocyte development and selection.
Organism : Mus musculus
GEO-ID : GDS1934
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- Compared Group :
- wild type Vs TCR transgenic
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- Number of Nodes in the Network : 2
- Number of Nodes passing Cut-Off : 100
- PValue Cut-Off : 5.97091202507727e-05
- Fold Change Cut-Off : 2.17
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Positively selected H-2b T cell receptor transgenic thymocytes (MG-U74A)
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GEO Description :
Analysis of positively selected T cell receptor (TCR) transgenic thymocytes from H-2b animals. T lymphocyte development involves TCR-mediated positive selection that ensures the survival of potentially useful T cells. Results provide insight into T lymphocyte development and selection.
Organism : Mus musculus
GEO-ID : GDS1933
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- Compared Group :
- wild type Vs TCR transgenic
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- Number of Nodes in the Network : 49
- Number of Nodes passing Cut-Off : 100
- PValue Cut-Off : 0.00023317696468439
- Fold Change Cut-Off : 2.13
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Vectorless gravity effect on T cell activation
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GEO Description :
Analysis of T cells costimulated with concanavalin A and anti-CD28 antibody in a vectorless gravity environment, which approximates true freefall or microgravity experienced in spaceflight. Results provide insight into the molecular basis of the altered immune function experienced by astronauts.
Organism : Homo sapiens
GEO-ID : GDS2035
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- Compared Group :
- donor 5 Vs donor 2
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- Number of Nodes in the Network : 48
- Number of Nodes passing Cut-Off : 100
- PValue Cut-Off : 0.000685562321450561
- Fold Change Cut-Off : 2.33
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- Compared Group :
- donor 2 Vs donor 4
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- Number of Nodes in the Network : 51
- Number of Nodes passing Cut-Off : 100
- PValue Cut-Off : 0.00127217348199338
- Fold Change Cut-Off : 2.37
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Imatinib effects on chronic myelogenous leukemia CD34+ cells
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GEO Description :
Comparison of purified bone marrow CD34+ cells from imatinib-treated chronic myelogenous leukemia (CML) patients and healthy donors.
Organism : Homo sapiens
GEO-ID : GDS838
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- Compared Group :
- control Vs imatinib
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- Number of Nodes in the Network : 51
- Number of Nodes passing Cut-Off : 100
- PValue Cut-Off : 0.000636180629953742
- Fold Change Cut-Off : 2.02
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DISCLAIMER:
The interactions, networks, list of genes/molecules or any other information presented here, is HYPOTHETICAL in nature and is based on information collected from public as well as other sources, and is analyzed by certain automated mining and analysis software workflows. Strandlife Science Pvt.Ltd. or the Editors of PathwayWorld offer this information with NO CLAIMS of accuracy and WARRANTIES of any kind, and DO NOT Accept liability or legal responsibility for losses allegedly caused by using this information.
GeneSpring® is a registered trademark of Agilent Technologies.
GeneSpring® is developed on AVADIS™ from Strand Life Sciences
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